Obesity and Addiction: Theories and Concepts

Obesity and Addiction Theories and ConceptsAs a want-to-be sure birdfeeder and as an individual susceptible to diabetes through a prevalent family history, I was intrigued by the article wherefore One Cream Cake Leads To other published in The Scientist. It caught my eye to learn that possibly there was a scientific reason behind my appetites of Starkbucks Frappucinos and Insomnias Smores Deluxe cookies and whitethornbe there is a valid and researched explanation as to why, when experience of overwhelming these touch officular treats, even when full, is it like a bitter cloying ending? Is this a minor case of a nutrient inclination? Is there some biochemical reason as to why matchless feels they must make much and must have it often? rear end it be lack of discipline to keep these things a reoccurring part of my f be even when attempting to make my consume habits cleaner and more nutritious?Why One Cream Cake Leads To Another, begins to answer these questions. A chroni c high-fat regimen is thought to desensitize the witticism to the feeling of satisfaction that one ordinarily gets from a meal, causing a person to overeat in fix to achieve the same high again. Newer research however, suggests that this desensitization actually begins in the gut itself, where production of a satiety factor, which normally tells the brain to go eating, becomes dialed down by the repeated intake of high-fat forage for thought. High-fat foods produce an endorphin reaction in the brain when they hit the taste buds the gut as well sends auspicates directly to the brain to catch our feeding behavior.Mice nourished via gastric feeding tubes, which bypass the mouth, depict a surge in dopaminea neurotransmitter promoting reinforcement in the brains reward circuitrysimilar to that go through by those eating normally. This dopamine surge occurs in response to feeding in some(prenominal) mice and humans. moreover evidence suggests that dopamine signaling in the b rain is wanting(predicate) in obese people. Ivan de Araujo, a professor of psychiatry at the Yale school of Medicine, has now discovered that obese mice on a chronic high-fat nutriment also have a muted dopamine response when receiving adipose food via a direct tube to their stomachs.To determine the nature of the dopamine-regulating signal emanating from the gut, Araujo and his team searched for possible candidates. When you look at animals chronically exposed to high-fat foods, you expose high levels of almost every circulating factorleptin, insulin, triglycerides, glucose, et cetera, he said. But one class of signaling molecule is suppressed. Of these, Araujos primary candidate was oleoylethanolamide(OEA), food-intake modulators . Not only is the factor produced by intestinal cells in response to food, he said, but during chronic high-fat exposure, the downsizing levels seemed to somehow match the suppression that we saw in dopamine release.It is not clear why a chronic h igh-fat diet suppresses the production of oleoylethanolamide. But once the vicious make pass starts, it is hard to break beca spend the brain is receiving its information subconsciously, said Daniele Piomelli, a professor at the University of California, Irvine, and director of dose discovery and development at the Italian Institute of Technology in Genoa. We eat what we like, and we think we argon conscious of what we like, but I think what others be indicating is that there is a deeper, non-whiteer berth to likinga side that were not aware of, Piomelli said. Because it is an ignorant drive, you cannot control it. Put another way, even if you could trick your taste buds into enjoying low-fat yogurt, youre contradictoryly to trick your gut.So if eating has much to do with biochemical and people dealing with obesity have a lack thereof, at what point is one addicted to food? Tuomisto, T Hetherington, Mm Morris, Mf Tuomisto, Mt Turjanmaa, V Lappalainen, R. (1999) study was to analyse similar affective, physiological, and behavioral variables in chocolate addicts and control subjects. Method Sixteen addicts and 15 control subjects took part in two laboratory experiments in which their heart rate, salivation, and self-reported responses were measured. Results In the bearing of external chocolate cues, chocolate addicts were more aroused, reported greater cravings, experienced more veto affect, and also ate more chocolate than control subjects. Self-report measures on eating attitudes and behavior, body image, and depression confirmed that a affinity exists between chocolate colony and problem eating. Chocolate addicts showed more deviant eating behaviors and attitudes than controls, and were also significantly more depressed. Discussion Chocolate addicts whitethorn be considered to be a parallel with addicts generally, because they differ from controls in craving for chocolate, eating behavior, and psychopathology (in respect of eating and affect).Accor ding to Corwin and Grigson (2009), food colony is a pervasive, yet controversial, topic that has gained recent attention in two lay media and the scientific literature. The goal of this series of articles is to use a crew of preclinical and clinical data to determine whether foods, like drugs of cry, can be addictive, the conditions under which the addiction develops, and the underlying neurophysiological substrates. Operational definitions of addiction that have been used in the treatment of human disorders and to guide research in both humans and animals are beed, and an overview of the symposium articles is provided. We propose that specific foods, especially those that are rich in fat and/or swag, are capable of promoting addiction-like behavior and neuronal change under certain conditions. That is, these foods, although highly palatable, are not addictive per se but become so pursuit a restriction/binge pattern of custom. Such consummatory patterns have been associated with increase risk for comorbid conditions much(prenominal) as obesity, early weight gain, depression, anxiety, and substance abuse as well as with turn and treatment challenges. The topic of food addiction bears study, therefore, to develop fresh approaches to clinical intervention and to advance our grounds of basic mechanisms involved in loss of control.Ifland JR1, Preuss HG, Marcus MT, Rourke KM, Taylor WC, Burau K, Jacobs WS, Kadish W, Manso G. (2009), study found the pursuance Overeating in industrial societies is a significant problem, linked to an change magnitude incidence of overweight and obesity, and the resultant adverse health consequences. We advance the shot that a possible explanation for overeating is that processed foods with high concentrations of sugar and other keen sweeteners, refined carbohydrates, fat, salt, and caffeine are addictive substances. Therefore, some people lose control over their ability to regulate their consumption of such foods. The loss of control over these foods could account for the global epidemic of obesity and other metabolic disorders. We assert that overeating can be described as an addiction to refined foods that conforms to the DSM-IV criteria for substance use disorders. To examine the hypothesis, we relied on experience with self-identified refined foods addicts, as well as precise reading of the literature on obesity, eating behavior, and drug addiction. Reports by self-identified food addicts illustrate behaviors that conform to the 7 DSM-IV criteria for substance use disorders. The literature also supports use of the DSM-IV criteria to describe overeating as a substance use disorder. The observational and empirical data strengthen the hypothesis that certain refined food consumption behaviors meet the criteria for substance use disorders, not unlike tobacco and alcohol. This hypothesis could lead to a new diagnostic category, as well as therapeutic approaches to changing overeating behaviors.I n drug addiction, the transition from casual drug use to dependence has been linked to a shift away from positive reinforcement and toward negative reinforcement. That is, drugs ultimately are relied on to prevent or relieve negative states that otherwise result from abstinence (e.g., withdrawal) or from adverse environmental circumstances (e.g., stress). Recent tempt has suggested that this dark side shift also is a key in the development of food addiction. Initially, palatable food consumption has both positively reinforcing, pleasurable effects and negatively reinforcing, comforting effects that can aggressively normalize organism responses to stress. Repeated, intermittent intake of palatable food may instead amplify brain stress circuitry and downregulate brain reward pathways such that continued intake becomes obligatory to prevent negative emotional states via negative reinforcement. Stress, anxiety and depressed mood have shown high comorbidity with and the potential to t ake off bouts of addiction-like eating behavior in humans. Animal models indicate that repeated, intermittent rag to palatable foods can lead to emotional and somatic signs of withdrawal when the food is no longer available, tolerance and dampening of brain reward circuitry, exacting seeking of palatable food despite potentially aversive consequences, and relapse to palatable food-seeking in response to anxiogenic-like stimuli. The neurocircuitry identified to date in the dark side of food addiction qualitatively resembles that associated with drug and alcohol dependence. The present review summarizes Bart Hoebels groundbreaking conceptual and empirical contributions to understanding the lineament of the dark side in food addiction along with tie in work of those that have followed him.( Parylak SL1, Koob GF, Zorrilla EP. 2011)So what stands to question, after all this secondary data analysis, is this just another way of demonizing fat? Is food addiction a fact or is it fiction an excuse built on monuments of nihility? Must one really hope for another scientific revelation, to cut through bad eating habits? Though many factors go into the food we intake, how much, how often, and how we allow or will not obtain enjoyment from it, there are also non-chemical factors. Such as, keep an open and level head round yourself when searching for a food high, it can mean more than your online weight or health, it can mean your life.